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產(chǎn)品詳情

  • 產(chǎn)品名稱：5HT1B Blocking Peptide for STJ500004 peptide (STJ503613)

  • 產(chǎn)品型號(hào)：STJ503613-250
  • 產(chǎn)品廠商：ST john's laboratory
  • 產(chǎn)品文檔：
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簡(jiǎn)單介紹：
5HT1B Blocking Peptide for STJ500004 peptide (STJ503613)
詳情介紹：
Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: 5HT1B Blocking Peptide for STJ500004 is synthetically produced from the 160-260 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Htr1b
Gene ID: 15551
Uniprot ID: 5HT1B_MOUSE
Immunogen Region: 160-260
Specificity: This blocking peptide is recommended for use in combination with 5HT1B antibody, STJ500004
Immunogen: Synthetic peptide taken within amino acid region 160-260 on rat 5HT1B
Tissue Specificity Predominantly expressed in striatum and Purkinje cells.
Post Translational Modifications Phosphorylated. Palmitoylated.
Function G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Regulates the release of 5-hydroxytryptamine, dopamine and acetylcholine in the brain, and thereby affects neural activity, nociceptive processing, pain perception, mood and behavior. Besides, plays a role in vasoconstriction of cerebral arteries.
Peptide Name 5-Hydroxytryptamine Receptor 1b
5-Ht-1b
5-Ht1b
Serotonin Receptor 1b
Database Links Reactome: R-MMU-390666
Reactome: -MMU-418594
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Peptide Names 5-Hydroxytryptamine Receptor 1b protein
5-Ht-1b protein
5-Ht1b protein
Serotonin Receptor 1b protein
Htr1b protein
5ht1b protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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